drugset / Trial / NCT01907308

Trebananib (AMG 386) in Combination With Docetaxel for Advanced Urothelial Carcinoma

NCT01907308

NaSingle-groupOpen-labelTreatment

Summary

This study plans to learn more about the combination of AMG 386 and docetaxel for the treatment of advanced urothelial cancer. Subjects are being asked to be in this research study because they have advanced urothelial cancer which has progressed after treatment with a platinum-based therapy. The hypothesis is that AMG 386 will increase the historical response rate of docetaxel as a single agent.

Timeline

Start
2014-02
Primary completion
2014-04
Completion
2014-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 75 mg/m2 Intravenous
Subject Trebananib Peptide 30 mg/kg Intravenous

Indications