drugset / Trial / NCT01907334
Dose-Response of Salmeterol in Children
Phase 4
Completed
10 enrolled
University of Florida
Teva Branded Pharmaceutical Products R&D, Inc. · collab
RandomizedCrossoverSingle-blind
Summary
To examine whether a breathing test (methacholine challenge using impulse oscillometry) can be used to tell the difference between two different doses of an inhaled drug, salmeterol, delivered by Advair in children with asthma
Timeline
- Start
- 2013-08
- Primary completion
- 2014-05
- Completion
- 2014-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluticasone | Other / unclassified | 100 ug | Inhaled |
| Comparator | Fluticasone | Other / unclassified | 200 ug | Inhaled |
| Comparator | Salmeterol | Other / unclassified | 50 ug | Inhaled |
| Comparator | Salmeterol | Other / unclassified | 100 ug | Inhaled |
| Comparator | Methacholine | Diagnostic / imaging agent | 0.25 mg/ml | Inhaled |
| Comparator | Methacholine | Diagnostic / imaging agent | 1 mg/ml | Inhaled |
| Comparator | Methacholine | Diagnostic / imaging agent | 4 mg/ml | Inhaled |
| Comparator | Methacholine | Diagnostic / imaging agent | 16 mg/ml | Inhaled |
| Comparator | Methacholine | Diagnostic / imaging agent | 64 mg/ml | Inhaled |
| Comparator | Salbutamol | Unknown | — | Inhaled |