drugset / Trial / NCT01908114

To Develop, Implement and Evaluate the Polio Demonstration Project Comprising of a Community Based Intervention Package for Polio Eradication in Pakistan

NCT01908114 ↗

RandomizedFactorialOpen-labelPrevention

Summary

The objective of the projects is to Develop and implement a Package of interventions that will comprise of an augmented communication and counseling strategy coupled with private sector involvement and a combined Oral Polio Vaccine and Inject able Polio Vaccine approach during the Polio campaigns followed by the evaluation of this project for acceptability, feasibility and effectiveness of the intervention Package.

Timeline

Start
2013-07
Primary completion
2017-07
Completion
2021-12

Outcome

Met primary endpoint

paper The estimated OPV coverage was 75% in arm A compared with 82% in arm B (difference vs arm A 6·6%; 95% CI 4·8-8·3) PMID 28495264 ↗

paper overall p<0·0001 PMID 28495264 ↗

paper a strategy of community mobilisation and targeted community-based health and immunisation camps during polio immunisation campaigns was successful in increasing vaccine coverage PMID 28495264 ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject Inactivated Polio Vaccine Vaccine — Other
Subject Oral Polio Vaccine Vaccine — Oral

Indications