Drugs / Inactivated Polio Vaccine
last change May 2025 re-read 2 minutes ago

Inactivated Polio Vaccine

Vaccine

Developed for
poliomyelitis
Investigated by
Sanofi Pasteur, a Sanofi Company · Centers for Disease Control and Prevention · World Health Organization · Aga Khan University · Bandim Health Project · Beijing Center for Disease Control and Prevention
+25 more · Beijing Institute of Biological Products Co Ltd. · Bill and Melinda Gates Foundation · China National Biotec Group Company Limited · Chinese Academy of Medical Sciences · Danish Council for Development Research · Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control · Institut Pasteur · Institute Pedro Kouri, Ministry of Public Health (Cuba) · International Cooperation with Developing Countries · LG Chem · London School of Hygiene and Tropical Medicine · Medical Research Council Unit, The Gambia · National Institute for the Control of Pharmaceutical and Biological Products, China · National Institutes of Health, Pakistan · PATH · Pakistan Ministry of Health · Pan American Health Organization · Peking University · Peshawar Medical College · Research Institute for Development · San Lucas Hospital, Ponce, Puerto Rico · Sanofi · Trust for Vaccines and Immunization, Pakistan · UNICEF · University Hospital, Ghent

Trials 19 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT01997632 Nov 2013 → May 2014 poliomyelitis University Hospital, Ghent Completed No outcome recorded
Phase 1 NCT01048190 Aug 2008 → Mar 2009 poliomyelitis Chinese Academy of Medical Sciences Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00885157 Apr → Oct 2009 poliomyelitis Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT03169725 May 2017 → Jan 2019 poliomyelitis LG Chem Completed No outcome recorded
Phase 33 trials
Phase 3 NCT01389687 Jul 2011 → Jan 2012 poliomyelitis Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 3 NCT00348387 Jun 2006 → Sep 2008 poliomyelitis Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 3 NCT00258843 Nov 2005 → Feb 2006 poliomyelitis Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 410 trials
Phase 4 NCT04051736 Mar → Dec 2018 China National Biotec Group Company Limited Completed No outcome recorded
Phase 4 NCT03286803 Aug 2017 → Apr 2019 poliomyelitis Aga Khan University Unknown No outcome recorded
Phase 4 NCT02005536 Dec 2013 → Sep 2014 poliomyelitis Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 4 NCT01847872 Jul 2013 → Apr 2015 poliomyelitis London School of Hygiene and Tropical Medicine Completed No outcome recorded
Phase 4 NCT01908114 Jul 2013 → Jul 2017 poliomyelitis Aga Khan University Unknown No outcome recorded
Phase 4 NCT01475539 Nov 2011 → May 2013 poliomyelitis Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 4 NCT01278433 Dec 2010 → Dec 2011 poliomyelitis Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 4 NCT01244464 Nov 2010 → Jun 2011 poliomyelitis Sanofi Completed No outcome recorded
Phase 4 NCT00893906 May 2009 → Dec 2012 influenza PATH Completed No outcome recorded
Phase 4 NCT00168662 Mar 1995 → Jan 2006 measles Bandim Health Project Completed No outcome recorded
Phase not applicable2 trials
NCT00137696 Jul 2003 → Jul 2004 poliomyelitis Centers for Disease Control and Prevention Completed No outcome recorded
NCT00260312 Aug 2001 → Jan 2003 Pan American Health Organization Completed No outcome recorded
Also used as a comparator or background therapy in 14 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT03614533 Comparator Dec 2018 → Aug 2019 typhoid fever University of Maryland, Baltimore Completed No outcome recorded
Phase 2 NCT00604058 Comparator Jan → Sep 2008 poliomyelitis Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT06947499 Comparator May 2025 → Nov 2026 expected diphtheria, haemophilus infectious disease, hepatitis B virus infection, pertussis +2 LG Chem Recruiting No outcome recorded
Phase 2/3 NCT01810731 Comparator Apr 2014 HIV infectious disease, influenza, malaria, poliomyelitis +1 Centers for Disease Control and Prevention Withdrawn No outcome recorded
Phase 35 trials
Phase 3 NCT05163561 Comparator Jan 2022 → Apr 2023 poliomyelitis Serum Institute of India Pvt. Ltd. Completed No outcome recorded
Phase 3 NCT05386810 Comparator Nov 2020 → Oct 2022 poliomyelitis Sinovac Biotech Co., Ltd Completed No outcome recorded
Phase 3 NCT04429295 Comparator Jun 2020 → Feb 2021 Rotavirus infection, diphtheria, haemophilus meningitis, hepatitis B virus infection +3 Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 3 NCT01813604 Comparator Nov 2012 → Nov 2013 poliomyelitis Centers for Disease Control and Prevention Completed No outcome recorded
Phase 3 NCT00290342 Comparator Jan 2006 → Jan 2007 diphtheria, tetanus GlaxoSmithKline Completed No outcome recorded
Phase 45 trials
Phase 4 NCT04998344 Comparator Apr 2021 → Dec 2024 influenza University of Bergen Unknown No outcome recorded
Phase 4 NCT03723837 Comparator Nov 2018 → Jun 2019 poliomyelitis Tribhuvan University Teaching Hospital, Institute Of Medicine. Completed No outcome recorded
Phase 4 NCT03202719 Comparator Nov 2017 → Oct 2019 poliomyelitis Centers for Disease Control and Prevention Completed No outcome recorded
Phase 4 NCT01680679 Comparator May 2012 → May 2014 influenza University of Colorado, Denver Completed No outcome recorded
Phase 4 NCT00934245 Comparator Sep 2009 → Jul 2012 influenza Wayne Sullender, M.D. Completed No outcome recorded

Evidence & citations 12 cited values

Every value below carries the sentence it was read from. 38 sources stand behind the page.

FieldValueCited text
Known as Inactivated Polio Vaccine “introduction of inactivated polio vaccine (IPV) in combination with OPV” PMID 28495264 Jun 2017
11

Inactivated Polio Vaccine (IPV)” NCT01847872

NCT01813604

NCT04051736

NCT00168662

NCT04998344

NCT03723837

NCT01810731

NCT00137696

NCT00934245

NCT06947499

NCT00893906

Known as fIPV “Fractional dose (one-fifth of full intramuscular dose) of inactivated poliovirus vaccine (fIPV) administered intradermally is used as IPV dose-sparing strategy.” PMID 32798224 Apr 2021
Known as IMOVAX Polio “Commercialized IPV based on Salk strain (Imovax Polio). Should be injected by intramuscular three injections in the anterolateral aspect of thigh at 6, 10 and 14 weeks of age.” NCT03169725
7

“fractional doses of sanofi pasteur's IMOVAX Polio injected intradermally” NCT00604058

“sanofi pasteur's IMOVAX Polio injected intradermally” NCT00885157

NCT01244464

NCT01997632

NCT00290342

NCT01278433

NCT02005536

Known as IMOVAX Polio (IPV) vaccine IMOVAX Polio (IPV) vaccineNCT00604058
Known as Inactivated Poliomyelitis Vaccine Inactivated Poliomyelitis Vaccine (IPV)-(Oral Poliomyelitis Vaccine) (OPV)-OPV (Sequential 1)” NCT01475539
3

NCT00258843

NCT01048190

NCT04429295

Known as inactivated poliovirus vaccine “A Phase 4, Randomized Trial to Assess the Safety and Immunogenicity of Inactivated Poliovirus Vaccine When Given Concomitantly With Measles and Rubella Combined Vaccine and...” NCT01847872
7

“The purpose of this study was to evaluated the effectiveness of inactivated poliovirus vaccine at a vaccine schedule that is commonly used in developing countries.” NCT00260312

Inactivated Poliovirus Vaccine - control vaccine produced by Sanofi.” NCT05386810

inactivated poliovirus vaccine (IPV)” NCT00934245

NCT03614533

NCT03286803

NCT03202719

NCT01680679

Known as IPV “Children born from September 1994 to January 1996 were randomized into two groups receiving either two doses of measles vaccine at 6 and 9 months or one dose of inactivated...” PMID 10342702 Apr 1999
11

“This was a follow-up study conducted in 2020 assessing changes in levels of type 2 poliovirus-neutralizing antibodies 2 years postimmunization in children who received...” PMID 37368349 Jan 2024

“will be administered along with inactivated poliovirus vaccine (IPV) on first 3 visits in both cohorts” NCT00137696

“with either the 2008-09 northern hemisphere IIV3 or an inactivated polio vaccine (IPV).” PMID 30689757 Oct 2019

“introduction of inactivated polio vaccine (IPV) in combination with OPV” PMID 28495264 Jun 2017

“Inactivated poliovirus vaccine (IPV) at 14 weeks and 18 months of age” NCT03202719

“Inactivated poliovirus vaccine (IPV), trivalent” NCT01680679

“Inactivated Poliovirus Vaccine (IPV)” NCT03614533

“Inactivated Polio Vaccine (IPV)” NCT03723837

“Inactivated Polio Vaccine (IPV)” NCT01847872

“Inactivated polio vaccine (IPV)” NCT00934245

“inactivated polio vaccine (IPV)” NCT01813604

Known as Poliomyelitis Vaccine inactivated “Poliomyelitis Vaccine (Inactivated), produced by Serum Institute of India Pvt. Ltd., is a sterile suspension of three types of inactivated poliovirus: Type 1 (Mahoney), Type 2...” NCT05163561
1

NCT00348387

Known as Sabin IPV “A domestic Sabin strain-based inactivated poliovirus vaccine (Sabin IPV) was approved by China Food and Drug Administration in 2017” PMID 33810904 Mar 2021
Known as SP059 “The aim of the study is to assess the immunogenicity and safety of SP059 as a three-dose primary and booster vaccination in Japanese infants aged 3 through 68 months.” NCT01389687
1

“The aim of the study is to assess the immunogenicity of SP059 (IMOVAX POLIO®: Inactive Poliovirus Vaccine) vaccine against poliovirus and safety after fifth dose.” NCT02005536

Modality Vaccine “inactivated polio vaccineNCT00137696
Route Intramuscular “0.5 mL, intramuscular (IM)” NCT00258843