drugset / Trial / NCT01909856
The Efficacy and Safety of Palonosetron in Preventing the Gastrointestinal Reactions Induced by 3-day Highly Emetogenic Chemotherapy
RandomizedCrossoverQuadruple-blindPrevention
Summary
This study is to assess the efficacy and safety of palonosetron in preventing the acute and delayed emesis induced by 3-day highly emetogenic chemotherapy. A double-blind, crossover design is used and granisetron is the positive control.
Timeline
- Start
- 2011-10
- Primary completion
- 2014-04
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Granisetron | Other / unclassified | 3 mg | — |
| Subject | Palonosetron | Other / unclassified | 0.25 mg | — |
| Background | Cisplatin | Other / unclassified | 25 mg/m2 | — |
| Background | Dexamethasone | Small molecule | 10 mg | — |