drugset / Trial / NCT01918761

Dacomitinib + Pemetrexed for Patients With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC)

NCT01918761

Phase 1 Terminated 5 enrolled Central European Cooperative Oncology Group
NaSingle-groupOpen-labelTreatment

Summary

To identify a dose of dacomitinib in combination with pemetrexed that is safe and tolerated as determined by the incidence of DLTs (dose limiting toxicities).

Timeline

Start
2013-07-30
Primary completion
2016-09-15
Completion
2016-09-15

Drugs

EvaluationDrugModalityDoseRoute
Subject DACOMITINIB ANHYDROUS Small molecule 45 mg Oral
Background Pemetrexed Small molecule 500 mg/m2 Intravenous