drugset / Trial / NCT01937598

Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2D

NCT01937598

Phase 3 Completed 16 enrolled Michael A. Nauck
RandomizedCrossoverDouble-blindBasic science

Summary

Objectives: To quantify differences in control of glycemia (primary objective) and the secretion of endogenous incretin hormones (secondary objective) comparing sitagliptin or placebo added to pre-existing therapy with liraglutide and metformin

Timeline

Start
2013-08
Primary completion
2014-04
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Sitagliptin Small molecule 100 mg
Background Liraglutide Peptide 1.2 mg