drugset / Trial / NCT01939691

Macular Edema Nepafenac vs. Difluprednate Uveitis Trial

NCT01939691

RandomizedParallel-groupSingle-blindTreatment

Summary

Macular edema is a condition in which there is swelling in the macula, the part of the retina that gives you your best vision. This swelling can cause your vision to decline. When diagnosed early and treated, you vision usually can be preserved. However, if the swelling goes untreated for a long time, it can cause permanent vision loss. We think that the three eye drop regimens in this study, difluprednate, difluprednate plus nepafenac, and prednisolone acetate plus nepafenac, might be effective in treating uveitic macular edema. Patients who enter this study are randomized to one of the three regimens and followed for 24 weeks.

Timeline

Start
2018-09-12
Primary completion
2020-03-31
Completion
2020-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Difluprednate Small molecule 0.05 % Other
Subject Nepafenac Other / unclassified 0.1 % Other
Subject Prednisolone Other / unclassified 1 % Other