drugset / Trial / NCT01939691
Macular Edema Nepafenac vs. Difluprednate Uveitis Trial
Phase 4
Terminated
9 enrolled
University of California, San Francisco
Aravind Eye Hospitals, India · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
Macular edema is a condition in which there is swelling in the macula, the part of the retina that gives you your best vision. This swelling can cause your vision to decline. When diagnosed early and treated, you vision usually can be preserved. However, if the swelling goes untreated for a long time, it can cause permanent vision loss. We think that the three eye drop regimens in this study, difluprednate, difluprednate plus nepafenac, and prednisolone acetate plus nepafenac, might be effective in treating uveitic macular edema. Patients who enter this study are randomized to one of the three regimens and followed for 24 weeks.
Timeline
- Start
- 2018-09-12
- Primary completion
- 2020-03-31
- Completion
- 2020-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Difluprednate | Small molecule | 0.05 % | Other |
| Subject | Nepafenac | Other / unclassified | 0.1 % | Other |
| Subject | Prednisolone | Other / unclassified | 1 % | Other |