drugset / Trial / NCT01944033

β2-agonist Versus Ipratropium Bromide Associated With β2-agonists in Chronic Obstructive Pulmonary Disease Exacerbation

NCT01944033

Phase 3 Completed 250 enrolled University of Monastir
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The effectiveness of β2-agonists in the treatment of exacerbations of COPD is already established. The purpose of this study is to compare the effectiveness of the β2-agonists alone in nebulization with the association β2-agonists + Ipratropium bromide in the treatment of an acute exacerbation of COPD consulting the emergency departement based on the clinical and arterial blood gas.

Timeline

Start
2013-07
Primary completion
2016-07
Completion
2017-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ipratropium Small molecule 0.5 mg Inhaled
Subject Terbutaline Small molecule 5 mg Inhaled