drugset / Trial / NCT01944839

A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy

NCT01944839

Phase 3 Terminated 619 enrolled Ophthotech Corporation
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The objectives of this study are to evaluate the safety and efficacy of intravitreal administration of Fovista® administered in combination with Lucentis® compared to Lucentis® monotherapy in subjects with subfoveal choroidal neovascularization secondary to age-related macular degeneration (AMD).

Timeline

Start
2013-08
Primary completion
2016-12
Completion
2016-12

Drugs

EvaluationDrugModalityDoseRoute
Subject PEGPLERANIB SODIUM Aptamer 1.5 mg Intravitreal
Background Ranibizumab Monoclonal antibody 0.5 mg Intravitreal