drugset / Trial / NCT01949844

Artifact-Free High-Resolution Myocardial Perfusion MRI in Subjects With Abnormal Nuclear Myocardial Perfusion Studies

NCT01949844

NaSingle-groupOpen-labelBasic science

Summary

This is a pilot study in a patient population with suspected coronary artery disease (CAD) as defined by the presence of a prior abnormal nuclear (PET/SPECT) myocardial perfusion scan. In this study design, PET/SPECT will serve as the comparative standard for presence of myocardial ischemia. We intend to determine the accuracy of an improved magnetic resonance imaging (MRI) technique for detection of myocardial ischemia in subjects with suspected CAD. This is not a study to specifically evaluate the efficacy or safety of the drugs but rather the diagnostic performance of the improved cardiac MRI procedure.

Timeline

Start
2014-05-16
Primary completion
2017-01-15
Completion
2017-10-23

Drugs

EvaluationDrugModalityDoseRoute
Background Gadoversetamide Diagnostic / imaging agent 0.1 mmol Intravenous
Background Regadenoson Diagnostic / imaging agent 0.4 mg Intravenous