drugset / Trial / NCT01950481

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

NCT01950481

Phase 1 Completed 36 enrolled Novartis Pharmaceuticals
Non-randomizedParallel-groupOpen-labelTreatment

Summary

Pharmacokinetics and safety of 750 mg of LDK378 given once orally in subjects with impaired hepatic function and healthy subjects with normal hepatic function.

Timeline

Start
2014-01
Primary completion
2016-09
Completion
2016-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Ceritinib Small molecule 750 mg Oral

Indications

No indication recorded.