drugset / Trial / NCT01958190

Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&Sirolimus

NCT01958190

Phase 4 Completed 196 enrolled Foundation for Liver Research
RandomizedParallel-groupOpen-labelTreatment

Summary

In this study we compare long term renal function in liver transplantation recipients treated with standard dose extended-release tacrolimus alone and recipients treated with a combination of low dose extended-release tacrolimus and low dose sirolimus. The hypothesis is that the patients treated with the combination have better long term renal function than the patients treated with standard dose tacrolimus alone.

Timeline

Start
2011-02-07
Primary completion
2021-05-20
Completion
2021-05-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Sirolimus Small molecule
Comparator Tacrolimus Small molecule
Comparator Prednisone Other / unclassified 7.5 mg

Indications