drugset / Trial / NCT01958190
Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&Sirolimus
RandomizedParallel-groupOpen-labelTreatment
Summary
In this study we compare long term renal function in liver transplantation recipients treated with standard dose extended-release tacrolimus alone and recipients treated with a combination of low dose extended-release tacrolimus and low dose sirolimus. The hypothesis is that the patients treated with the combination have better long term renal function than the patients treated with standard dose tacrolimus alone.
Timeline
- Start
- 2011-02-07
- Primary completion
- 2021-05-20
- Completion
- 2021-05-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sirolimus | Small molecule | — | — |
| Comparator | Tacrolimus | Small molecule | — | — |
| Comparator | Prednisone | Other / unclassified | 7.5 mg | — |