Study of Long-Acting Acetaminophen in Postoperative Dental Pain

Summary

The purpose of the study is to evaluate the efficacy and safety of acetaminophen ER 1500 mg (two 750 mg tablets) over 10 to 12 hours in the dental pain model following third molar extraction(s) and to evaluate the pharmacokinetics of acetaminophen ER 1500 mg (two 750 mg tablets) in a sub-group of subjects.

Timeline

Start

2013-10

Primary completion

2014-04

Completion

2014-04

Outcome

Met primary endpoint

registry Placebo vs ACE ER 1500 mg; p <0.001; Least Squares Mean Difference 25.241 (95% CI 19.669 to 30.813) NCT01960114 ↗

Drugs

Indications