Effect of Cyclodextrin on Sensory Nerve Activity: A Novel Anti-tussive Therapy

Summary

The investigators want to see whether the test drug in this research study, 2-hydroxypropyl-beta-cyclodextrin (2HPBCD), might potentially be able to improve cough in healthy volunteers. The investigators are initially recruiting healthy volunteers such as who are free from any respiratory disease and not on any concurrent medication, so there are no confusing effects from pre-existing respiratory symptoms or disease, nor interaction of any medication with the test drug.

Timeline

Start

2016-08

Primary completion

2017-08

Completion

2017-12

Outcome

Outcome not reported

Stopped: “Study has not been able to start due to difficulty in obtaining an intravenous formulation of cyclodextrin (intravenous 2HPBCD) suitable for man”

Drugs

Indications

No indication recorded.