An Efficacy Study of Stain Control of a 67% Sodium Bicarbonate Containing Toothpaste on Chlorhexidine Tooth Staining

NCT01962493 ↗

Phase 4 Completed 160 enrolled GlaxoSmithKline

RandomizedParallel-groupSingle-blindPrevention

Summary

The aim of this study is to compare the stain effect on teeth of twice daily brushing with a 67% sodium bicarbonate containing toothpaste versus standard toothpaste (not containing sodium bicarbonate) for six weeks whilst using a chlorhexidine digluconate 0.2% mouthwash.

Timeline

Start: 2013-09
Primary completion: 2013-11
Completion: 2013-11

Publications

Akwagyiram I, Butler A, Maclure R, Colgan P, Yan N, Bosma ML. A randomised clinical trial to evaluate the effect of a 67 % sodium bicarbonate-containing dentifrice on 0.2 % chlorhexidine digluconate mouthwash tooth staining. BMC Oral Health. 2016 Aug 25;16(1):79. doi: 10.1186/s12903-016-0271-3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Background	Chlorhexidine gluconate	Other / unclassified	0.2 %	Other

Indications

No indication recorded.