drugset / Trial / NCT01962896

A Phase II Study of Sirolimus and Erlotinib in Recurrent/Refractory Germ Cell Tumors

NCT01962896 ↗

Phase 2 Terminated 4 enrolled Theodore Laetsch
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to find out if the combination of an mTOR inhibitor (sirolimus) with an EGFR inhibitor (erlotinib) is effective at treating relapsed or refractory germ cell tumors, and to find out what the side-effects of this regimen are.

Timeline

Start
2014-01-08
Primary completion
2017-06-13
Completion
2018-01-27

Outcome

Outcome not reported

Stopped (Enrollment): “Low accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Erlotinib Small molecule — —
Subject Sirolimus Small molecule — —

Indications