drugset / Trial / NCT01963702

A Phase II Trial of Exploring the Predictive Factors of TX and XELOX Regimen in the First Line Treatment of MGC

NCT01963702 ↗

Phase 2 Unknown 120 enrolled Fudan University
RandomizedCrossoverOpen-labelTreatment

Summary

Platinum, fluorouracil and taxane based regimen are all acceptable in the first line treatment of metastatic gastric cancer. The TX and XELOX regimen are two common regimen used in MGC. whichever regimen is used, the average response rate is less than 50%. So a rather part of patients can't get benefit from the treatment. It is urgent to find out the predictive factors of these regimens in order to get a higher response and better survival outcome.

Timeline

Start
2012-08
Primary completion
2013-12
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 1000 mg/m2 —
Comparator Oxaliplatin Small molecule 130 mg/m2 —
Subject docetaxol Unknown 60 mg/m2 —
Subject docetaxol Unknown 75 mg/m2 —

Indications