drugset / Trial / NCT01974518
Comparative Study of Rituximab Versus Combination of Rituximab and Intravenous Cyclophosphamide in Severe Pemphigus
Phase 3
Unknown
20 enrolled
Uprety Shraddha
Post Graduate Institute of Medical Education and Research, Chandigarh · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to compare the effectiveness of rituximab alone vs combination of rituximab and cyclophosphamide in the treatment of pemphigus not responding adequately to routine medications.
Timeline
- Start
- 2013-11
- Primary completion
- 2015-06
- Completion
- 2015-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclophosphamide | Other / unclassified | 750 mg | Intravenous |
| Comparator | Rituximab | Monoclonal antibody | 1 g | Intravenous |