Effect of Intravenous Dexmedetomidine on Analgesic Duration of Infraclavicular Block
Summary
The study will evaluate the effect of Dexmedetomidine sedation on the duration of infraclavicular block in patients scheduled for surgery of elbow, forearm and/or hand. All patients will receive infraclavicular block before the surgery and then they will be randomized to receive either Dexmedetomidine or Propofol sedation. Duration of the sensory block will be evaluated in recovery room, 24 and 48 hours after the surgery. Hypothesis: Primary: Dexmedetomidine sedation increases the duration of sensory infraclavicular block in patients scheduled for upper limb surgery. Secondary: Dexmedetomidine sedation * Gives an adequate level of sedation during the surgical procedure * Reduces the requirements of postoperative opioids * Improves the quality of sleep on the night of the surgery * Increases patients satisfaction regarding the anesthesia technique * Dexmedetomidine sedation is safe and easy to use * Dexmedetomidine sedation provides less respiratory depression during the procedure.
Timeline
- Start
- 2014-01
- Primary completion
- 2016-07
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 0.2 mg/kg | Intravenous |
| Subject | Dexmedetomidine | Other / unclassified | 0.5 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 50 ug/kg | Intravenous |
| Comparator | Propofol | Small molecule | 100 ug/kg | Intravenous |
Indications
No indication recorded.