drugset / Trial / NCT01983800

AnaConDa Long Term Sedation Study

NCT01983800

Completed 60 enrolled University Health Network, Toronto
RandomizedParallel-groupOpen-labelTreatment

Summary

Heavy sedation or sleep is a common problem within the intensive care unit (ICU) using our standard intravenous medications. This commonly leads to confusion, low blood pressure, slow wake up and removal of the artificial breathing tube (extubation), which prolongs ICU stay. Using inhaled volatile anesthetic agents are likely to improve these patient outcomes. This unique project is the first North American study looking at using volatiles for patients who need longer-term ICU sedation. This project has excellent potential at lowering these complications and improving quality of care, which will lower patient ICU stay and healthcare costs.

Timeline

Start
2013-07
Primary completion
2018-02
Completion
2020-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Isoflurane Other / unclassified Inhaled
Comparator Midazolam Small molecule Intravenous
Comparator Propofol Small molecule Intravenous

Indications

No indication recorded.