drugset

drugset / Trial / NCT01997112

PAracetamol Treatment in Hypertension: Effect on Blood Pressure (PATH-BP) Study

NCT01997112 ↗

Phase 4 Completed 100 enrolled University of Edinburgh British Heart Foundation · collab National Health Service, United Kingdom · collab

RandomizedCrossoverQuadruple-blindSupportive care

Summary

The purpose of this study is to examine if chronic paracetamol dosing increases blood pressure in patients with known high blood pressure.

Timeline

Start: 2014-01
Primary completion: 2019-06-04
Completion: 2019-10

Publications

MacIntyre IM, Turtle EJ, Farrah TE, Graham C, Dear JW, Webb DJ; PATH-BP (Paracetamol in Hypertension-Blood Pressure) Investigators*. Regular Acetaminophen Use and Blood Pressure in People With Hypertension: The PATH-BP Trial. Circulation. 2022 Feb 8;145(6):416-423. doi: 10.1161/CIRCULATIONAHA.121.056015. Epub 2022 Feb 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Acetaminophen	Small molecule	1 g	—

Indications