drugset / Trial / NCT01997164

Study of Intravitreal (IVT) REGN910-3 and IVT REGN910 in Patients With Either Neovascular ("Wet") Age Related Macular Degeneration (AMD) or Diabetic Macular Edema (DME)

NCT01997164

Phase 1 Completed 20 enrolled Regeneron Pharmaceuticals
Non-randomizedSingle-groupOpen-labelBasic science

Summary

The primary objective of the study is to investigate the safety and tolerability of intravitreal (IVT) REGN910-3 and IVT REGN910 in patients with neovascular age-related macular degeneration (AMD), and separately in patients with diabetic macular edema (DME).

Timeline

Start
2014-11
Primary completion
2015-10
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Subject REGN910-3 Unknown Intravitreal
Subject nesvacumab Monoclonal antibody Intravitreal
Background Aflibercept Protein / enzyme biologic Intravitreal