drugset / Trial / NCT01997840

ACY-1215 (Ricolinostat) in Combination With Pomalidomide and Low-dose Dex in Relapsed-and-Refractory Multiple Myeloma

NCT01997840

Phase 1/2 Terminated 103 enrolled Celgene Corporation
NaSingle-groupOpen-labelTreatment

Summary

Phase 1b: To evaluate the side effects and determine the best dose of ACY-1215 in combination with Pomalidomide and low-dose dexamethasone in patients with relapsed-and-refractory multiple myeloma. Phase 2: To determine the overall response rate of ACY-1215 in combination with Pomolidomide and low-dose dexamethasone in patients with relapsed-and-refractory multiple myeloma

Timeline

Start
2014-03-01
Primary completion
2024-02-29
Completion
2024-02-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Ricolinostat Small molecule 160 mg
Background Dexamethasone Small molecule 40 mg
Background Pomalidomide Other / unclassified 4 mg

Indications