drugset / Trial / NCT01998789
Everolimus Post Orthotopic Liver Transplant
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the efficacy of an everolimus conversion (EVR) protocol as compared to the standard tacrolimus (TAC) based protocol in liver transplant recipients, as determined by renal function, rejection rates, and progression to fibrosis (in HCV positive subjects). Additionally, safety profile and tolerability of these regimens will be assessed.
Timeline
- Start
- 2013-10
- Primary completion
- 2018-06
- Completion
- 2019-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Everolimus | Small molecule | 1 mg | Oral |
| Comparator | Tacrolimus | Small molecule | — | — |
Indications
No indication recorded.