drugset / Trial / NCT01999530
The Effects of Prazosin on Dopamine in Healthy Humans: A PET Pilot Study
Phase 1
Completed
20 enrolled
Centre for Addiction and Mental Health
Ontario Lung Association · collabPfizer · collab
NaSingle-groupOpen-labelBasic science
Summary
The purpose of this study is to find out whether short term treatment with a antihypertensive medication prazosin, can influence the levels of a dopamine in the brain. We will examine the levels of dopamine in the the brain using Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI). We hypothesize that there will be no significant changes in dopamine levels in healthy individuals taking prazosin.
Timeline
- Start
- 2013-11
- Primary completion
- 2016-08
- Completion
- 2016-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Prazosin | Unknown | 15 mg | — |
Indications
No indication recorded.