drugset / Trial / NCT02001519

Additional 4 Cycles of Cisplatin (CDDP4) in Patients With Triple Negative Breast Cancer for Neoadjuvant Chemotherapy

NCT02001519 ↗

Phase 2 Completed 88 enrolled Asan Medical Center
NaSingle-groupOpen-labelTreatment

Summary

Achievement of pathologic complete response is important prognosticator to predict long term outcome in triple negative cancer. The efficacy of adding 4 cycles of cisplatin (CDDP4) is to be investigated whether addtional pathologic complete response is achieved for those triple negative breast cancer patients who recieved 4 cycles of adriamycin with cyclophosphamide(AC4) but did not reach clinical complete response during the course of neoadjuvant therapy.

Timeline

Start
2012-03
Primary completion
2014-02
Completion
2014-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 75 mg/m2 —
Subject Cyclophosphamide Other / unclassified 600 mg/m2 —
Subject Doxorubicin Other / unclassified 60 mg/m2 —

Indications