drugset / Trial / NCT02005211
A Two-part Single and Multiple Dose Study to Assess the Safety , Pharmacokinetics and Effects of AZD3293 in Healthy Japanese Young and Elderly Volunteers
RandomizedParallel-groupDouble-blindBasic science
Summary
This study consists of two parts, ie, single dose part with young healthy subjects (Part 1) and single and multiple dose part with elderly healthy subjects (Part 2), to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD3293 following single and multiple ascending dose administration to healthy subjects.
Timeline
- Start
- 2013-12
- Primary completion
- 2014-07
- Completion
- 2014-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lanabecestat | Small molecule | 15 mg | Oral |
| Subject | Lanabecestat | Small molecule | 50 mg | Oral |
| Subject | Lanabecestat | Small molecule | 150 mg | Oral |
Indications
No indication recorded.