drugset / Trial / NCT02007837

Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial

NCT02007837

RandomizedParallel-groupQuadruple-blindPrevention

Summary

Hypertensive disorders of pregnancy (HDP) are with 50.000 deaths every year one of the major causes of maternal mortality worldwide, especially in low and middle income countries. This trial aims to determine whether a daily dose of combined low-dose aspirin, calcium, vitamin D3, folic acid and vitamin B12 in pregnancy reduces the incidence of pregnancy-induced hypertension in women at risk. Secondary and tertiary objectives include other maternal and neonatal outcomes.

Timeline

Start
2018-01
Primary completion
2018-04
Completion
2018-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule 80 mg
Subject Calcium carbonate Other / unclassified 1.2 g
Subject Vitamin B12 Other / unclassified 1000 ug
Subject Vitamin D Other / unclassified 600 iu
Subject folic acid Other / unclassified 5 mg