drugset / Trial / NCT02008448

Endomyocardial Botulinum Toxin Injection in Patients With Persistent Atrial Fibrillation

NCT02008448

RandomizedParallel-groupDouble-blindTreatment

Summary

The investigators have conducted a prospective, double-blind, randomized study to assess the comparative safety and efficacy of two different ablation strategies, PVI plus linear lesions (LL) plus botulinum toxin injection versus PVI plus linear lesions (LL), in patients with persistent or longstanding persistent AF. Results were assessed with the use of an implanted monitoring device (IMD).

Timeline

Start
2013-06
Primary completion
2015-12
Completion
2016-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Botulinum toxin Protein / enzyme biologic Other