drugset / Trial / NCT02024633
Combination of Icotinib and Gemcitabine as First-line Treatment in Pancreatic Cancer
NaSingle-groupOpen-labelTreatment
Summary
Research Hypothesis: icotinib administered in combination with gemcitabine has an acceptable safety profile in subjects with locally advanced, unresectable or metastatic pancreatic adenocarcinoma.The primary objective is to determine the safety profile of icotinib in combination with gemcitabine in subjects with locally advanced, unresectable or metastatic pancreatic adenocarcinoma.
Timeline
- Start
- 2013-12
- Primary completion
- 2015-12
- Completion
- 2016-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gemcitabine | Small molecule | 1000 mg/m2 | Intravenous |
| Subject | Icotinib | Small molecule | 125 mg | — |
| Subject | Icotinib | Small molecule | 250 mg | — |
| Subject | Icotinib | Small molecule | 375 mg | — |