drugset / Trial / NCT02026869

Vaginal Administration of Metformin in PCOS Patients.

NCT02026869

Phase 0 Unknown 200 enrolled Assiut University
RandomizedFactorialOpen-labelTreatment

Summary

Polycystic ovary syndrome is a common cause of irregular periods, poor ovulation and delay in achieving pregnancy. Certain drugs may help improve ovarian activity in such women as metformin. Oral administration of metformin is accompanied by undesirable side effects. The vagina proved to be a good alternative to the oral route for other drugs. Using metformin through the vagina and avoidance of such side effects, while maintaining its effectiveness, would help women to better tolerate this drug.

Timeline

Start
2013-01
Primary completion
2013-06
Completion
2014-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metformin Small molecule 850 mg Oral