Eclampsia and Posterior Reversible Encephalopathy Syndrome (PRES):

Summary

This is a double blinded, placebo-controlled trial to determine if IV dexamethasone more quickly than placebo assists resolution of Posterior Reversible Encephalopathy Syndrome (PRES) encountered in eclamptic patients. All patients regardless of assignment to placebo or steroid will receive standard therapy to include magnesium sulfate, blood pressure medications and diuretics. We hypothesize that the addition of dexamethasone to standard therapy will accelerate CNS recovery more quickly than standard management without dexamethasone.

Timeline

Start

2012-02

Primary completion

2013-12

Completion

2013-12

Outcome

Outcome not reported

Stopped (Enrollment): “Difficulty recruiting, only one participant in 18 months, rarity of event”

Drugs

Indications