Prevention of Infection in Closed Fractures: Cefazolin Versus Vancomycin

Summary

The purpose of this study is to compare the incidence rate of infection in surgical patients with closed fractures treated prophylactically with Cefazolin versus Vancomycin in the peri-operative period. The hypothesis of this study is that patients undergoing surgical treatment for closed fractures who are treated prophylactically with Vancomycin will have a lower incidence rate of infection than patients who are treated prophylactically with Cefazolin.

Timeline

Start

2009-10

Primary completion

2015-06

Completion

2017-12

Drugs

Indications