drugset / Trial / NCT02029118
Acupoint Application in Patients With Stable Angina Pectoris (AASAP)
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Hypothesis: acupoint application is effective for managing chronic stable angina pectoris. Aim: to evaluate the efficacy and safety of acupoint application on the specific acupoints for chronic stable angina pectoris. Design: A Randomized, Controlled,Double Blind trial. 200 participants will be included. Four arms: herbal medicine application on acupoint group , placebo application on acupoint group , herbal medicine application on non-acupoint group and placebo application on non-acupoint group.
Timeline
- Start
- 2012-10
- Primary completion
- 2015-05
- Completion
- 2015-08
Outcome
Met primary endpoint
paper The HAA group had significantly fewer angina attacks than the PAA group (P<0.05). PMID 34387828 ↗
Publications
- Li DH, Xie J, Ren YL, Zheng H, Lyu JL, Leng JY, Zhang LL, Zhang J, Fan HL, Liang FR. Effectiveness and Safety of Acupoint Application of Guan Xin Su He Pill () for Patients with Chronic Stable Angina Pectoris: A Multi-Center, Randomized Controlled Trial. Chin J Integr Med. 2021 Nov;27(11):838-845. doi: 10.1007/s11655-021-2870-3. Epub 2021 Aug 13.
- Ren Y, Li D, Zheng H, Lv J, Leng J, Zhang L, Zhang J, Fan H, Liang F. Acupoint application in patients with chronic stable angina pectoris: study protocol of a randomized, double-blind, controlled trial. Evid Based Complement Alternat Med. 2014;2014:619706. doi: 10.1155/2014/619706. Epub 2014 Aug 27.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Guan Xin Su He Pill | Unknown | — | — |
| Background | Aspirin | Small molecule | 100 mg | — |
| Background | Atorvastatin | Small molecule | 20 mg | — |
| Background | Metoprolol | Other / unclassified | 25 mg | — |
| Background | Ramipril | Small molecule | 5 mg | — |
Indications
No indication recorded.