drugset / Trial / NCT02037347

Study to Evaluate the Use of Palifermin to Treat Toxic Epidermal Necrolysis

NCT02037347

Phase 1/2 Terminated 1 enrolled Brett King Swedish Orphan Biovitrum · collab
NaSingle-groupOpen-labelTreatment

Summary

To test the ability of palifermin (a recombinant human keratinocyte growth factor) to decrease mucocutaneous injury and to promote epithelial repair in Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis Overlap, diseases in which there is extensive sloughing of the skin and mucosa, including that of the eyes, gastrointestinal tract, respiratory and genitourinary systems.

Timeline

Start
2010-10
Primary completion
2014-12
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Palifermin Protein / enzyme biologic 60 ug/kg Intravenous