drugset / Trial / NCT02039791

Study of Nimotuzumab in Combination With Neoadjuvant Chemotherapy for Cervical Cancer

NCT02039791

Phase 2 Unknown 20 enrolled Biotech Pharmaceutical Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

Nimotuzumab is a humanized monoclonal antibody against epidermal growth factor receptor (EGFR). Clinical trials are ongoing globally to evaluate Nimotuzumab in different indications. Nimotuzumab has been approved to treat squamous cell carcinoma of head and neck (SCCHN), glioma and nasopharyngeal carcinoma in different countries. The clinical phaseⅡtrial is designed to assess the resection rate and pathological complete response of nimotuzumab plus carboplatin and paclitaxel in patients with cervical cancer.

Timeline

Start
2013-01
Primary completion
2016-06
Completion
2016-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule
Subject Nimotuzumab Monoclonal antibody 200 mg
Subject Paclitaxel Small molecule 175 mg/m2

Indications