drugset / Trial / NCT02039791
Study of Nimotuzumab in Combination With Neoadjuvant Chemotherapy for Cervical Cancer
NaSingle-groupOpen-labelTreatment
Summary
Nimotuzumab is a humanized monoclonal antibody against epidermal growth factor receptor (EGFR). Clinical trials are ongoing globally to evaluate Nimotuzumab in different indications. Nimotuzumab has been approved to treat squamous cell carcinoma of head and neck (SCCHN), glioma and nasopharyngeal carcinoma in different countries. The clinical phaseⅡtrial is designed to assess the resection rate and pathological complete response of nimotuzumab plus carboplatin and paclitaxel in patients with cervical cancer.
Timeline
- Start
- 2013-01
- Primary completion
- 2016-06
- Completion
- 2016-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carboplatin | Small molecule | — | — |
| Subject | Nimotuzumab | Monoclonal antibody | 200 mg | — |
| Subject | Paclitaxel | Small molecule | 175 mg/m2 | — |