Topiramate: Long-Term Maintenance of Weight Loss Induced by Low-Calorie Diet in Obese Subjects

Summary

The purpose of this study is to determine the efficacy and safety of topiramate (96 mg or 192 mg daily) as compared to placebo in maintaining weight loss in obese subjects who participated in an eight week intensive non-pharmacologic weight loss program. The primary efficacy endpoint will be the percent change in body weight from enrollment visit to week 60.

Timeline

Start

2000-08

Primary completion

2002-06

Completion

2002-06

Outcome

Outcome not reported

Stopped: “Study was terminated early as sponsor wanted to develop an improved formulation.”

Drugs

Indications