RCT (Randomized Controlled Trial) of IV Acetaminophen for Post Cesarean Pain Relief

NCT02046382 ↗

Phase 4 Completed 132 enrolled TriHealth Inc.

RandomizedParallel-groupTriple-blindSupportive care

Summary

This study is being done to evaluate the scheduled use of intravenous (IV) acetaminophen among cesarean section patients. The study hopes to find out if patients who receive scheduled IV acetaminophen for 48 hours following delivery have lower self-reported pain scores and use less narcotic pain medication than patients who do not receive IV acetaminophen.

Timeline

Start: 2014-01
Primary completion: 2016-12
Completion: 2017-05

Outcome

Met primary endpoint

paper significantly reduced when compared with the placebo group (47 mg vs 65 mg of oxycodone; P = .034). PMID 28455085 ↗

Publications

Altenau B, Crisp CC, Devaiah CG, Lambers DS. Randomized controlled trial of intravenous acetaminophen for postcesarean delivery pain control. Am J Obstet Gynecol. 2017 Sep;217(3):362.e1-362.e6. doi: 10.1016/j.ajog.2017.04.030. Epub 2017 Apr 25.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Acetaminophen	Small molecule	1000 mg	Intravenous

Indications

No indication recorded.