drugset / Trial / NCT02046395
Effect of Renin-angiotensin-system Blockade on Urinary Free Light Chains in Patients With Type 2 Diabetes Mellitus
NaSingle-groupOpen-labelDiagnostic
Summary
The purpose of this study is to study the effect of blocking the renin angiotensin system on urinary free light chain excretion as compared to urine microalbumin creatinine ratio in subjects with type 2 diabetes. The long term goal is to assess urinary free-light chains as a biomarker of earlier detection of kidney function impairment in subjects with diabetes mellitus.
Timeline
- Start
- 2012-01
- Primary completion
- 2019-12
- Completion
- 2019-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Amlodipine | Other / unclassified | — | — |
| Background | Hydralazine | Small molecule | — | — |
| Background | Hydrochlorothiazide | Unknown | — | — |
| Background | Terazosin | Small molecule | — | — |