drugset / Trial / NCT02057107

SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

NCT02057107 ↗

Phase 2 Completed 40 enrolled Heath Skinner
RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this trial is to examine the addition of docetaxel on disease progression, metastasis and survival of patients otherwise treated with SBRT and cetuximab alone. To better resolve the impact of the experimental treatment the presence/absence of prior cetuximab treatment will be determine before assigning treatment to either cetuximab and SBRT only or cetuximab, SBRT, and docetaxel.

Timeline

Start
2013-07-03
Primary completion
2019-03-15
Completion
2019-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetuximab Monoclonal antibody 250 mg/m2 —
Subject Docetaxel Small molecule 25 mg/m2 —