Haloperidol vs Conventional Therapy for Gastroparesis

NCT02057549 ↗

Phase 4 Terminated 36 enrolled The University of Texas Health Science Center, Houston

RandomizedParallel-groupDouble-blindTreatment

Summary

Randomized controlled trial comparing haloperidol combined with conventional therapy and conventional therapy alone in patients with symptomatic gastroparesis.

Timeline

Start: 2012-11
Primary completion: 2016-11
Completion: 2016-11

Outcome

Met primary endpoint

Stopped: “PI left institution”

paper CONCLUSIONS: Haloperidol as an adjunctive therapy is superior to placebo for acute gastroparesis symptoms. PMID 28646590 ↗

Publications

Roldan CJ, Chambers KA, Paniagua L, Patel S, Cardenas-Turanzas M, Chathampally Y. Randomized Controlled Double-blind Trial Comparing Haloperidol Combined With Conventional Therapy to Conventional Therapy Alone in Patients With Symptomatic Gastroparesis. Acad Emerg Med. 2017 Nov;24(11):1307-1314. doi: 10.1111/acem.13245. Epub 2017 Jul 26.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Haloperidol	Other / unclassified	5 mg	Intravenous