Auranofin in Decreasing Pain in Patients With Paclitaxel-Induced Pain Syndrome

Summary

This randomized pilot clinical trial studies whether auranofin will relieve pain following paclitaxel in patients who have previously experienced paclitaxel-induced pain. Auranofin is a drug given by mouth to treat other diseases such as rheumatoid arthritis, and is being studied to see if it will decrease pain following paclitaxel.

Timeline

Start

2014-02-19

Primary completion

2015-11-11

Completion

2016-11-11

Outcome

Missed primary endpoint

registry analysis (superiority test); Arm I (Auranofin) vs Arm II (Placebo); p = 1.0; Fisher Exact NCT02063698 ↗

registry analysis (superiority test); Arm I (Auranofin) vs Arm II (Placebo); p = 0.44; Equal variance t-test NCT02063698 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Auranofin	Small molecule	—	Oral

Indications

No indication recorded.