drugset / Trial / NCT02064920

Computerized Cognition Testing in Participants With Mild Alzheimer's Disease (AD) Treated With Donepezil (MK-0000-318)

NCT02064920

Phase 2 Completed 36 enrolled Merck Sharp & Dohme LLC
RandomizedParallel-groupTriple-blindDiagnostic

Summary

This study aims to determine whether the Cogstate testing battery can detect improvements in cognitive function in participants with mild AD. The primary hypothesis is that for one of the Cogstate battery tests, One Card Learning (OCL), the standard deviation associated with the change from baseline in OCL measurements after 12 weeks of donepezil and placebo treatments is =\<0.1

Timeline

Start
2014-04-22
Primary completion
2016-07-13
Completion
2016-07-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Donepezil Small molecule 10 mg Oral

Indications