Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropathy

Summary

The purpose of the study is to determine whether clonidine gel is an effective treatment for reducing the pain associated with painful diabetic neuropathy.

Timeline

Start

2014-03

Primary completion

2015-03

Completion

2015-03

Outcome

Missed primary endpoint

registry analysis (superiority test); Clonidine Gel 0.1% vs Placebo; p = 0.4503; Mixed Models Analysis; note: MMRM imputing for missing data NCT02068027 ↗

Publications

• Serednicki WT, Wrzosek A, Woron J, Garlicki J, Dobrogowski J, Jakowicka-Wordliczek J, Wordliczek J, Zajaczkowska R. Topical clonidine for neuropathic pain in adults. Cochrane Database Syst Rev. 2022 May 19;5(5):CD010967. doi: 10.1002/14651858.CD010967.pub3.

Drugs

Indications