drugset / Trial / NCT02074358
A Study to Assess the Effects of 2 Prothrombin Complex Concentrates on the Pharmacodynamics of Apixaban in Healthy Adult Subjects
RandomizedCrossoverOpen-labelBasic science
Summary
The purpose of this study is to assess the effect of two 4-Factor PCC formulations on Apixaban pharmacodynamics in healthy adult subjects.
Timeline
- Start
- 2014-02
- Primary completion
- 2014-04
- Completion
- 2014-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Apixaban | Small molecule | 10 mg | Oral |
| Subject | Beriplex P/N | Protein / enzyme biologic | 50 iu/kg | Intravenous |
| Subject | Cofact | Protein / enzyme biologic | 50 iu/kg | Intravenous |
Indications
No indication recorded.