Effect of Linagliptin on Vascular Inflammation in Patients With Type 2 Diabetes Mellitus

Summary

Examination of the effect of Linagliptin versus placebo for 6 months on vascular inflammation of the carotic artery and on abdominal adipose tissue inflammation in patients with diabetes mellitus type 2. The effect will be assessed by FDG-PET scan. Furthermore the effect of Linagliptin on the vessel wall volume of the carotid artery will be assessed by MRI scan and biomarkers of vascular inflammation will be analyzed in blood samples.

Timeline

Start

2014-08

Primary completion

2015-09

Completion

2015-11

Drugs

Indications