drugset / Trial / NCT02078024
Efficacy of Ivermectin and Albendazole Against Onchocerciasis in the Volta Region, Ghana
RandomizedFactorialOpen-labelDiagnostic
Summary
We will examine whether a combination of Ivermectim (IVM) plus Albendazole (ALB) compared to IVM alone given annually, which is the current standard for mass drug administration (MDA), is more effective in sterilizing adult worms. We will also address whether IVM plus ALB given twice per year is superior to IVM given once per year or twice per year.
Timeline
- Start
- 2014-06
- Primary completion
- 2018-06
- Completion
- 2018-06-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Albendazole | Small molecule | 400 mg | — |
| Subject | Albendazole | Small molecule | 800 mg | — |
| Subject | Ivermectin | Small molecule | 200 ug/kg | Oral |