Ondansetron for Bipolar Disorder and Alcohol Use Disorders

Summary

The purpose of the study is to determine if ondansetron, as an add-on therapy, is associated with reduced depressive symptoms and alcohol use in outpatients with bipolar disorder (BPD), cyclothymic disorder, schizoaffective disorder (bipolar type) and major depressive disorder (MDD) with mixed features. The investigators will also use blood samples to determine if the genotype for the serotonin transporter gene is associated with response to ondansetron.

Timeline

Start

2014-02

Primary completion

2018-05

Completion

2018-05

Drugs

Indications