drugset / Trial / NCT02084485
PH-797804 LPS Study in Healthy Volunteers
RandomizedCrossoverDouble-blindBasic science
Summary
The study was performed to assess the effect of PH-797804 on neutrophils (white cells) in the sputum after a challenge with an endotoxin (inhaled LPS). Neutrophils are a sign of inflammation and PH-797804 is being developed as a potential anti-inflammatory treatment for patients with Chronic Obstructive Pulmonary Disease (COPD).
Timeline
- Start
- 2006-09
- Primary completion
- 2008-03
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PH-797804 | Small molecule | 30 mg | Oral |
Indications
No indication recorded.